Новости за 26.03.2024

Researchers have discovered a protein called SEL1L that plays a critical role in clearing collagen from tissue, and which may be a therapeutic target to help prevent fibrosis, scar tissue that interferes with organ function. The paper provides clues that could lead to drug development for diseases like lung fibrosis which have no therapeutic options currently.

A new study shows virus-like particle can effectively 'shock and kill' latent HIV reservoir in those living with chronic HIV.

A new study suggest that using CXCL9 and CXCL10-producing dendritic cells alongside immunotherapy can be a promising strategy to overcome treatment resistance and improve clinical outcomes for patients with non-small cell lung cancer.

Study reveals how proteins direct nerve cell precursors to turn into specialized neurons.

Researchers have now developed standards and calibrations for optical microscopes that allow quantum dots to be aligned with the center of a photonic component to within an error of 10 to 20 nanometers (about one-thousandth the thickness of a sheet of paper). Such alignment is critical for chip-scale devices that employ the radiation emitted by quantum dots to store and transmit quantum information.

Scientists have uncovered a unique mechanism that regulates the opening of stomata in plants. Phosphorylation of the amino acid Thr881 on the plasma membrane proton pump plays a key role in this process. The study paves the way for the targeted manipulation of plant physiology, with potential applications in agriculture and environmental sustainability.

Researchers have used machine learning to identify subgroups of trauma patients who are more likely to survive their injuries if treated with tranexamic acid. This treatment controls bleeding and thereby prevents death from hemorrhage. The team also identified subgroups of trauma patients who do not benefit from tranexamic acid. These findings should help guide treatment decisions after traumatic injury and provide trauma patients with more personalized care.

Researchers have identified a new potential target for the treatment of Alzheimer's disease -- PDE4B. The researchers observed that AD mice showed memory deficits in maze tests, but memory was unimpaired in AD mice with genetically reduced PDE4B activity.

High-power lasers are often used to modify polymer surfaces to make high-tech biomedical products, electronics and data storage components. Now researchers have discovered a light-responsive, inexpensive sulfur-derived polymer is receptive to low power, visible light lasers -- promising a more affordable and safer production method in nanotech, chemical science and patterning surfaces in biological applications.

Lewy body disease may be more common in middle-aged people than previously thought, according to a recent study. In the study, almost one in ten of over 50-year-olds were found to have tissue markers of Lewy body disease in the brain.

An orange dwarf star has yielded the tiniest 'starquakes' ever recorded, measured by an international team of scientists.

The xCT protein, which plays an important role as a transport molecule in the cell, could play a part in cancer treatment in the future, researchers have discovered. Their recent studies on mice show that targeting the protein can not only reduce tumor growth, it can also help regulate the inflammatory response and improve mood.

Nontraditional risk factors such as migraines are as important as traditional risk factors like high blood pressure for adults younger than ages 35-45, finds new study.

New research has shown the warming climate will turn Australia's soil into a net emitter of carbon dioxide (CO2), unless action is taken. Soil helps to keep the planet cool by absorbing carbon, however as the climate gets warmer its ability to retain carbon decreases -- and in some instances can start to release some carbon back into the air. A global research team has predicted the changes in the amount of carbon in Australia's soil between now and the year 2100.

The International Brain pH Project Consortium unveils groundbreaking findings in a large-scale animal model study, indicating altered brain pH and lactate levels as a transdiagnostic endophenotype in neuropsychiatric disorders with cognitive impairment. This collaborative effort, involving 131 researchers across six countries, challenges existing notions and may pave the way for novel strategies in understanding and addressing biologically diverse and debilitating disorders impacting cognitive function.

As authorities crack down on illicit drugs, experts have issued an alert on the use of the synthetic stimulant pentylone, as new research finds a 75% increase in detections across Australia.

Researchers have successfully transformed CO2 into methanol by shining sunlight on single atoms of copper deposited on a light-activated material, a discovery that paves the way for creating new green fuels.

Air pollution and night-time outdoor light each were associated with harmful effects on brain health, finds new study.

A study has identified a combination of medications that may improve blood flow within granulomas, benefiting drug delivery. The study leverages decades of cancer research to study tuberculosis-affected lung tissue and improve treatment.

When officials make tough calls on which areas to prioritize for conservation, biodiversity is often their top consideration. But there are several types of diversity, and not all of them overlap perfectly. In a new study, researchers analyzed 20-years' worth of U.S. Forest Service data and show that the simplest measure of diversity is the best predictor of healthy forest growth, providing a roadmap for quickly and efficiently protecting ecological resources.

Pairing cryptocurrency mining -- notable for its outsize consumption of carbon-based fuel -- with green hydrogen could provide the foundation for wider deployment of renewable energy, such as solar and wind power, according to a new study.

A new study has found human brains are getting bigger. The increased size may lead to a brain reserve, potentially reducing the risk of dementia.

Many parents recognize increasing mental health concerns among children, reflected by the 1 in 5 who say they're open to allowing a child to take a mental health day.