Новости за 09.06.2022

A drug currently used in just 1% of cancers has significant potential against the remaining 99%, according to a new study. Ivosidenib, or AG-120, is currently used against cancers that have a mutation in the IDH1 gene. However, study results show that Ivosidenib is also effective against unmutated, or 'wild-type' IDH1. The protein coded by the IDH1 gene in cancers helps cancer cells survive in a stressful tumor environment, so any inhibitor medication that could weaken this defense mechanism is considered a promising therapy.

A hotter ocean is a hungrier ocean -- at least as far as fish predators are concerned. Scientists have discovered predator impacts in the Atlantic and Pacific peak at higher temperatures. The effects cascade down to transform other life in the ocean, potentially disrupting balances that have existed for millennia.

Hydrogen peroxide (H2O2) is an important chemical, with a wide variety of applications. However, the current method used to manufacture H2O2 is expensive and generates a considerable amount of waste, making it an unsustainable approach. In this study, a group of researchers produced H2O2 from waste coffee grounds and tea leaves, and then demonstrated its industrial use. Their novel method proved to be simple, cost-effective, and most importantly, sustainable.

Intestinal flora plays an important role in health -- including mental health. Researchers have shown that probiotics can support the effect of antidepressants and help to alleviate depression.

Why are we so sure that the way we see people, situations and politics is accurate, and the way other people see them is foolishly wrong? The answer, according to new research lies in a region of the brain he calls the 'gestalt cortex,' which helps people make sense of information that is ambiguous or incomplete -- and dismiss alternative interpretations.

Researchers have developed a tiny, flexible neural probe that can be implanted for longer time periods to record and stimulate neural activity, while minimizing injury to the surrounding tissue. The probe would be ideal for studying small and dynamic areas of the nervous system like peripheral nerves or the spinal cord.

Those who are among the heaviest drinkers in England are four times more likely to smoke than the general population and should be prioritized by the government in its plans to achieve 'smoke-free' status by 2030, experts say.

A genetic variant that is present in nearly 30% of Greenlanders is linked to high cholesterol and an increased risk of cardiovascular disease, according to a new study.

Researchers now reveal that nature's storage solution first evolved in ancient microbes living on Earth between one and two billion years ago.

The Japan Aerospace Exploration Agency's Hayabusa2 mission returned uncontaminated primitive asteroid samples to Earth. A comprehensive analysis of 16 particles from the asteroid Ryugu revealed many insights into the processes that operated before, during and after the formation of the solar system, with some still shaping the surface of the present-day asteroid. Elemental and isotopic data revealed that Ryugu contains the most primitive pre-solar nebular (an ancient disk of gas and dust surrounding... Читать дальше...

Researchers have develop a silicon-based optical communications link that can improve data-intensive internet applications from video streaming services to high-capacity transactions for the stock market. This device could enable the next generation of optical interconnects for use in data-center networks that form the backbone of the internet.

Researchers have discovered that infiltrating gliomas, a common brain and spinal cord tumor, are shaped by their genetic evolution and microenvironment, a finding that could lead to more targeted treatments.

The tip of rotavirus B spike protein is not only totally different from the corresponding structure in rotavirus A and C, but also no other protein before had been reported to have this structure.

New evidence suggests that two major glaciers in the West Antarctic Ice Sheet (WAIS) are losing ice at the fastest rate for at least 5,500 years.

In biology, getting rid of stuff can be just as important as making it. A buildup of cells, proteins, or other molecules that are no longer needed can cause problems, so living things have evolved several ways to clean house.

One of the hallmarks of Parkinson's disease (PD) is the accumulation in the brain of a protein known as alpha-synuclein. A new study shines new light on the role of alpha-synuclein, uncovering a new function for the protein with relevance for PD and related conditions. The team's findings are published in Cell.

The Colorado River is in an extremely severe drought and has been for the last 22 years. To better understand this drought, researchers looked at the drought history within the Colorado River Basin. Previous studies have gone back 1,200 years, but this paper goes back 2,000 years. The findings, using paleo hydrology, show that there was an even more severe drought in the Colorado River Basin in the second century.

Researchers identify why the fast fashion business model creates waste and whether regulators can establish incentives for consumers and manufacturers are steps to reducing waste.

New research finds climate change is having an impact on how large whale species, including the critically endangered North Atlantic right whale, use habitats in the warming Gulf of Maine, showing that right whales' use of Cape Cod Bay has shifted significantly over the last 20 years.

Researchers found that airports situated in colder climates accumulated more pollutants like PM2.5 in the fall and winter, compared to airports in milder climates.

Palaeontologists have identified the remains of one of Europe's largest ever land-based hunters: a dinosaur that measured over 10m long and lived around 125 million years ago.

Scientists have finally cracked a problem that's frustrated chemists and physicists for years, potentially leading to a new age of powerful, efficient, and environmentally friendly technologies.

Moderate average drinkers with a pattern of binge drinking were almost five times more likely to experience multiple alcohol problems, researchers report.

Eating higher levels of fish, including tuna and non-fried fish, appears to be associated with a greater risk of malignant melanoma, suggests a large study of US adults.

As surveillance for ticks and the disease-causing germs they spread improves, so does Americans' access to knowledge about where the risk of tickborne disease is greatest. Experts have assembled new surveillance data into a report that offers up-to-date county-level maps of both where blacklegged ticks are prevalent and where they've been found infected with any of seven different disease-causing germs, or pathogens.