The Latest: 'Moonlight' wins best film drama Globe
The Globes, which split the top film winners into two categories, previously awarded "La La Land" the best film comedy or musical trophy.
Huppert won for her role as in the French film "Elle," which also won the best foreign language film award Sunday.
Casey Affleck has won the Golden Globe Award for best actor in a drama film for his portrayal of grieving father in "Manchester by the Sea."
Affleck's performance is considered one of the best of his career and he is considered a favorite to receive a best actor Oscar nomination later this month.
The musical about a jazz musician and an actress who fall in love as they struggle to establish their careers in Los Angeles won in all seven categories for which it was nominated.
The Globes splits its top honors for films into two categories, with the winner for best film drama to be announced later Sunday.
Streep said she was mortified during the presidential campaign by Trump's criticism of a disabled New York Times reporter, and called for people to support press rights as a check on Trump's power.
The actress anticipated blowback from Trump supporters, saying at one point during her speech, "''Hollywood is crawling with foreigners, so if you kick them all out you'll have nothing to watch but football and mixed martial arts."
Actor Chris Pine thanked Streep for her speech after the Globes returned from a commercial break.
The Golden Globe Awards don't have a formal segment honoring actors who have died in the past year, but this year's program did included homages to the recently departed Debbie Reynolds and Carrie Fisher.
The ceremony included a brief video montage of the mother-daughter duo during its ceremony, and Meryl Streep shared some of Fisher's words while accepting one of the evening's top honors, the Cecil B. DeMille Award for lifetime achievement.
Streep, who starred in the film adaptation of Fisher's book "Postcards from the Edge," mentioned Fisher at the close of her speech, recalling how she once told her, "Take your broken heart, make it into art."
The Netflix series had its name called back-to-back on Sunday night, with star Claire Foy winning the best actress in a television drama award.
The film stars Isabelle Huppert as the head of a successful video game company whose life takes strange turns.
The Disney film about a spunky rabbit who overcomes substantial odds to become a crime-solving police officer, stars Ginnifer Goodwin, Jason Bateman and Idris Elba.
Ryan Gosling has won the Golden Globe Award for best actor in a film comedy or musical.
The actor gave heartfelt thanks to his partner, Eva Mendes, thanking her for supporting him during the film while she was pregnant with their second child and caring for her sick brother.
Jimmy Fallon borrowed the traffic jam song-and-dance routine from "La La Land" to kick off the Golden Globe Awards, with a song-and-dance intro featuring cameos from Globes nominees Raimi Malek and John Travolta, among others.
Most stars don't make it inside the Beverly Hilton ballroom in time to eat and drink the 3:30 champagne dinner before the Golden Globes awards kicks off, but there were a few hungry and thirsty early birds this year.
Portman, a best actress nominee for motion picture drama for the film "Jackie," was instantly recognizable in a mustard yellow gown.
Helberg, who is up for a supporting actor nomination in that film, says he's looking forward to a boisterous and booze-filled evening at the Globes where "people drink and say more than they need to say."
A clear plastic rain cover over the red carpet has proved entirely unnecessary, and is only heightening heat that's in the upper 70s.
Despite the blue skies, a somber mood may dominate the evening in the first major Hollywood awards show since Donald Trump's election.